The red flour beetle, Tribolium castaneum, is a worldwide insect pest of stored products, particularly food grains, and a powerful model organism for developmental, physiological and applied entomological research on coleopteran species. Among coleopterans, T. castaneum has the most fully sequenced and annotated genome and consequently provides the most advanced genetic model of a coleopteran pest. The beetle is also easy to culture and has a short generation time. Research on this beetle is further assisted by the availability of expressed sequence tags and transcriptomic data. Most importantly, it exhibits a very robust response to systemic RNA interference (RNAi), and a database of RNAi phenotypes (iBeetle) is available. Finally, classical transposon-based techniques together with CRISPR/Cas-mediated gene knockout and genome editing allow the creation of transgenic lines. As T.
UCN-02 |
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| 564792 | MedKoo Biosciences | 1.0mg | EUR 520 |
NCT 02 |
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| 466234 | MedKoo Biosciences | 10.0mg | EUR 390 |
TA 02 |
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| B4924-10 | ApexBio | 10 mg | EUR 136 |
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Description: Stem Cell|HSC |
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TA 02 |
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| B4924-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 80.8 |
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Description: Stem Cell|HSC |
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TA 02 |
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| B4924-50 | ApexBio | 50 mg | EUR 290.4 |
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Description: Stem Cell|HSC |
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PU 02 |
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| B5687-10 | ApexBio | 10 mg | EUR 132 |
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Description: GPCR/G protein|5-HT Receptor |
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PU 02 |
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| B5687-25 | ApexBio | 25 mg | EUR 571.2 |
PU 02 |
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| B5687-5 | ApexBio | 5 mg | EUR 172.8 |
PU 02 |
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| B5687-50 | ApexBio | 50 mg | EUR 460 |
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Description: GPCR/G protein|5-HT Receptor |
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TA-02 |
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| B1215-25 | Biovision | each | EUR 679.2 |
TA-02 |
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| B1215-5 | Biovision | each | EUR 222 |
UCN-02 |
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| C4829-1 | ApexBio | 1 mg | EUR 436 |
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Description: TGF-β / Smad Signaling|PKC |
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UCN-02 |
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| C4829-5 | ApexBio | 5 mg | EUR 1528 |
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Description: TGF-β / Smad Signaling|PKC |
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TA-02 |
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| HY-100115 | MedChemExpress | 10mM/1mL | EUR 357.15 |
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Description: TA-02, an analog of SB 203580 (HY-10256), is a p38 MAPK inhibitor with an IC50 of 20 nM. TA-02 especially inhibits TGFBR-2. TA-02 exhibits similar cardiogenic properties as SB 203580 and SB 202190 (HY-10295)[1]. |
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UCN-02 |
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| HY-108262 | MedChemExpress | 1mg | EUR 779.23 |
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Description: UCN-02 (7-epi-Hydroxystaurosporine) is a selective protein kinase C (PKC) inhibitor produced by Streptomyces strain N-12, with IC50s of 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively. UCN-02 (7-epi-Hydroxystaurosporine) displays cytotoxic effect on the growth of HeLa S3 cells[1][2]. |
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OATD-02 |
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| HY-155108 | MedChemExpress | Get quote | Ask for price |
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Description: OATD-02 is an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and 2. OATD-02 is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 abolishes tumor immunosuppression induced by both arginases. OATD-02 can be used for melanoma study[1]. |
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ORN 02 |
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| HY-160228 | MedChemExpress | Get quote | Ask for price |
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Description: ORN 02 is a synthetic single-stranded U-rich RNA and contains 6 repeats of UUAU sequence motif. The AU-rich oligoribonucleotides (ORNs) are able to stimulate TLR8[1]. |
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OF-02 |
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| HY-145795 | MedChemExpress | 10 mg | EUR 1731.63 |
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Description: OF-02 is an alkenyl amino alcohol (AAA) ionizable lipid for highly potent in vivo mRNA delivery. |
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PU 02 |
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| MBS386011-100mg | MyBiosource | 100mg | EUR 635 |
PU 02 |
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| MBS386011-10mg | MyBiosource | 10mg | EUR 175 |
PU 02 |
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| MBS386011-25mg | MyBiosource | 25mg | EUR 270 |
PU 02 |
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| MBS386011-50mg | MyBiosource | 50mg | EUR 405 |
PU 02 |
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| MBS386011-5x100mg | MyBiosource | 5x100mg | EUR 2845 |
TA-02 |
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| MBS3602690-10mg | MyBiosource | 10mg | EUR 590 |
TA-02 |
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| MBS3602690-25mg | MyBiosource | 25mg | EUR 995 |
TA-02 |
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| MBS3602690-2mg | MyBiosource | 2mg | EUR 310 |
TA-02 |
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| MBS3602690-5mg | MyBiosource | 5mg | EUR 445 |
TA-02 |
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| MBS3602690-5x25mg | MyBiosource | 5x25mg | EUR 4160 |
UCN-02 |
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| MBS3843736-10mg | MyBiosource | 10mg | EUR 1905 |
UCN-02 |
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| MBS3843736-1mg | MyBiosource | 1mg | EUR 430 |
UCN-02 |
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| MBS3843736-5mg | MyBiosource | 5mg | EUR 1165 |
UCN-02 |
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| MBS3843736-5x10mg | MyBiosource | 5x10mg | EUR 8565 |
PU-02 |
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| MBS5759242-100mg | MyBiosource | 100mg | EUR 590 |
PU-02 |
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| MBS5759242-10mg | MyBiosource | 10mg | EUR 190 |
PU-02 |
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| MBS5759242-25mg | MyBiosource | 25mg | EUR 275 |
PU-02 |
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| MBS5759242-50mg | MyBiosource | 50mg | EUR 405 |
PU-02 |
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| MBS5759242-5mg | MyBiosource | 5mg | EUR 155 |
TA-02 |
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| MBS5750722-10mg | MyBiosource | 10mg | EUR 230 |
TA-02 |
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| MBS5750722-1mg | MyBiosource | 1mg | EUR 145 |
TA-02 |
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| MBS5750722-25mg | MyBiosource | 25mg | EUR 335 |
TA-02 |
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| MBS5750722-2mg | MyBiosource | 2mg | EUR 150 |
TA-02 |
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| MBS5750722-5mg | MyBiosource | 5mg | EUR 180 |
UCN-02 |
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| MBS5770148-5mg | MyBiosource | 5mg | EUR 915 |
UCN-02 |
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| MBS5770148-5x5mg | MyBiosource | 5x5mg | EUR 3970 |
SST-02 |
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| MBS5784208-INQUIRE | MyBiosource | INQUIRE | Ask for price |
IMM-02 |
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| MBS5775255-5mg | MyBiosource | 5(mg | EUR 915 |
IMM-02 |
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| MBS5775255-5x5mg | MyBiosource | 5x5(mg | EUR 3970 |
ELX-02 |
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| MBS5781219-5mg | MyBiosource | 5(mg | EUR 915 |
ELX-02 |
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| MBS5781219-5x5mg | MyBiosource | 5x5(mg | EUR 3970 |
TA-02 |
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| MBS387970-10mg | MyBiosource | 10mg | EUR 295 |
TA-02 |
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| MBS387970-1mg | MyBiosource | 1mg | EUR 130 |
TA-02 |
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| MBS387970-50mg | MyBiosource | 50mg | EUR 775 |
TA-02 |
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| MBS387970-5mg | MyBiosource | 5mg | EUR 210 |
TA-02 |
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| MBS387970-5x50mg | MyBiosource | 5x50mg | EUR 3480 |
UCN-02 |
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| T17198-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: UCN-02 |
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UCN-02 |
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| T17198-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: UCN-02 |
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UCN-02 |
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| T17198-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: UCN-02 |
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UCN-02 |
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| T17198-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: UCN-02 |
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UCN-02 |
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| T17198-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: UCN-02 |
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SST-02 |
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| T34707-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: SST-02 |
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SST-02 |
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| T34707-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: SST-02 |
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SST-02 |
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| T34707-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: SST-02 |
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SST-02 |
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| T34707-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: SST-02 |
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SST-02 |
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| T34707-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: SST-02 |
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ELX-02 |
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| T31616-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: ELX-02 |
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ELX-02 |
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| T31616-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: ELX-02 |
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ELX-02 |
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| T31616-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: ELX-02 |
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ELX-02 |
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| T31616-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: ELX-02 |
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ELX-02 |
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| T31616-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: ELX-02 |
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IMM-02 |
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| T25530-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: IMM-02 |
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IMM-02 |
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| T25530-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: IMM-02 |
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IMM-02 |
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| T25530-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: IMM-02 |
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IMM-02 |
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| T25530-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: IMM-02 |
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IMM-02 |
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| T25530-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: IMM-02 |
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TA-02 |
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| T4646-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: TA-02 |
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TA-02 |
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| T4646-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: TA-02 |
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TA-02 |
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| T4646-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: TA-02 |
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TA-02 |
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| T4646-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: TA-02 |
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TA-02 |
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| T4646-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: TA-02 |
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UCN-02 |
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| TRC-U130603-1MG | Toronto Research Chemicals | 1 mg | Ask for price |
UCN-02 |
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| U006-1MG | TOKU-E | 1 mg | EUR 221.09 |
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Description: 121569-61-7 |
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UCN-02 |
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| U006-5MG | TOKU-E | 5 mg | EUR 771.65 |
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Description: 121569-61-7 |
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UCN-02 |
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| U130603 | Toronto Research Chemicals | 1mg | EUR 1800 |
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Description: 121569-61-7 |
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ZNL-02-096 |
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| 533532 | MedKoo Biosciences | 5.0mg | EUR 850 |
OXF BD 02 |
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| B4918-10 | ApexBio | 10 mg | EUR 426.4 |
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Description: Chromatin/Epigenetics|Bromodomain |
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OXF BD 02 |
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| B4918-50 | ApexBio | 50 mg | EUR 1124.8 |
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Description: Chromatin/Epigenetics|Bromodomain |
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SPMIT.02 Antibody |
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| CSB-PA325241XA01SXV-02mg | Cusabio | 0.2mg | Ask for price |
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Description: Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) SPMIT.02 protein |
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SPMIT.02 Antibody |
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| CSB-PA325241XA01SXV-10mg | Cusabio | 10mg | Ask for price |
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Description: Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) SPMIT.02 protein |
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HTH-02-006 |
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| HY-156397 | MedChemExpress | Get quote | Ask for price |
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Description: HTH-02-006 is a NUAK2 inhibitor (IC50?=?126?nM). HTH-02-006 reduces levels of phosphorylated MYPT1 in HuCCT-1 cells. HTH-02-006 inhibits YAP-driven cell proliferation, hepatomegaly and tumorigenesis. HTH-02-006 also has antifibrotic protective effect[1][2]. |
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ORN 02 (sodium) |
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| HY-160228A | MedChemExpress | Get quote | Ask for price |
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Description: ORN 02 (sodium) is a synthetic single-stranded U-rich RNA and contains 6 repeats of UUAU sequence motif. The AU-rich oligoribonucleotides (ORNs) are able to stimulate TLR8[1]. |
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MM-02-57 |
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| HY-161166 | MedChemExpress | Get quote | Ask for price |
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Description: MM-02-57 is a covalent DDB1 CUL4A adaptor protein recruiter[1]. |
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MM-02-08 |
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| HY-161167 | MedChemExpress | Get quote | Ask for price |
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Description: MM-02-08 is the potent BRD4 degrader and binds to DDB1[1]. |
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GA-O-02 |
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| HY-145853 | MedChemExpress | Get quote | Ask for price |
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Description: GA-O-02, a 18β-Glycyrrhetinic acid derivative, is a potent antimicrobial and anti-inflammatory agent. GA-O-02 exerts anti-inflammation through the inhibition of NO, pro-inflammatory cytokines and chemokines. GA-O-02 displays a high antimicrobial activity against Gram-positive bacteria[1]. |
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TG-02 (SB1317) |
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| MBS386287-10mg | MyBiosource | 10mg | EUR 225 |
TG-02 (SB1317) |
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| MBS386287-25mg | MyBiosource | 25mg | EUR 345 |
TG-02 (SB1317) |
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| MBS386287-5mg | MyBiosource | 5mg | EUR 180 |
TG-02 (SB1317) |
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| MBS386287-5x25mg | MyBiosource | 5x25mg | EUR 1550 |
ELX-02 disulfate |
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| MBS3846181-10mg | MyBiosource | 10mg | EUR 2965 |
ELX-02 disulfate |
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| MBS3846181-1mg | MyBiosource | 1mg | EUR 630 |
ELX-02 disulfate |
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| MBS3846181-50mg | MyBiosource | 50mg | EUR 8600 |
ELX-02 disulfate |
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| MBS3846181-5mg | MyBiosource | 5mg | EUR 1770 |
ELX-02 sulfate |
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| MBS3846188-10mg | MyBiosource | 10mg | EUR 2965 |
ELX-02 sulfate |
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| MBS3846188-1mg | MyBiosource | 1mg | EUR 630 |
ELX-02 sulfate |
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| MBS3846188-50mg | MyBiosource | 50mg | EUR 8600 |
ELX-02 sulfate |
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| MBS3846188-5mg | MyBiosource | 5mg | EUR 1770 |
OXF BD 02 |
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| MBS3841610-10mg | MyBiosource | 10mg | EUR 290 |
OXF BD 02 |
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| MBS3841610-50mg | MyBiosource | 50mg | EUR 750 |
OXF BD 02 |
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| MBS3841610-5mg | MyBiosource | 5mg | EUR 210 |
OXF BD 02 |
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| MBS3841610-5x50mg | MyBiosource | 5x50mg | EUR 3370 |
ELX-02 disulfate |
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| MBS5756001-10mg | MyBiosource | 10mg | EUR 1740 |
ELX-02 disulfate |
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| MBS5756001-5mg | MyBiosource | 5mg | EUR 1155 |
ELX-02 disulfate |
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| MBS5756001-5x10mg | MyBiosource | 5x10mg | EUR 7675 |
ELX-02 sulfate |
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| MBS5771907-5mg | MyBiosource | 5mg | EUR 915 |
ELX-02 sulfate |
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| MBS5771907-5x5mg | MyBiosource | 5x5mg | EUR 3970 |
BMS-747158-02 |
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| MBS387863-10mg | MyBiosource | 10mg | EUR 750 |
BMS-747158-02 |
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| MBS387863-25mg | MyBiosource | 25mg | EUR 1440 |
BMS-747158-02 |
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| MBS387863-5mg | MyBiosource | 5mg | EUR 465 |
BMS-747158-02 |
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| MBS387863-5x25mg | MyBiosource | 5x25mg | EUR 6480 |
Mixture ME 02 |
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| MBS393941-500mg | MyBiosource | 500mg | EUR 630 |
ELX-02 disulfate |
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| T19306-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: ELX-02 disulfate |
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ELX-02 disulfate |
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| T19306-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: ELX-02 disulfate |
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ELX-02 disulfate |
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| T19306-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: ELX-02 disulfate |
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ELX-02 disulfate |
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| T19306-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: ELX-02 disulfate |
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ELX-02 disulfate |
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| T19306-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: ELX-02 disulfate |
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ELX-02 sulfate |
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| T19307-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: ELX-02 sulfate |
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ELX-02 sulfate |
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| T19307-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: ELX-02 sulfate |
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ELX-02 sulfate |
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| T19307-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: ELX-02 sulfate |
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ELX-02 sulfate |
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| T19307-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: ELX-02 sulfate |
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ELX-02 sulfate |
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| T19307-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: ELX-02 sulfate |
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OXF BD 02 |
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| T23115-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: OXF BD 02 |
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OXF BD 02 |
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| T23115-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: OXF BD 02 |
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OXF BD 02 |
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| T23115-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: OXF BD 02 |
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OXF BD 02 |
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| T23115-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: OXF BD 02 |
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OXF BD 02 |
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| T23115-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: OXF BD 02 |
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ZNL 02-096 |
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| T41163-10mg | TargetMol Chemicals | 10mg | Ask for price |
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Description: ZNL 02-096 |
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ZNL 02-096 |
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| T41163-1g | TargetMol Chemicals | 1g | Ask for price |
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Description: ZNL 02-096 |
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ZNL 02-096 |
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| T41163-1mg | TargetMol Chemicals | 1mg | Ask for price |
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Description: ZNL 02-096 |
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ZNL 02-096 |
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| T41163-50mg | TargetMol Chemicals | 50mg | Ask for price |
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Description: ZNL 02-096 |
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ZNL 02-096 |
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| T41163-5mg | TargetMol Chemicals | 5mg | Ask for price |
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Description: ZNL 02-096 |
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145867-02-3 |
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| TBZ1279 | ChemNorm | unit | Ask for price |
1961358-02-0 |
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| TBW00994 | ChemNorm | 10mg | Ask for price |
Recombinant Human P53 WT (HLA-A*02:01) Tetramer Protein |
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| RP02698 | Abclonal | 100μg | EUR 853.74 |
Monoclonal LST1 Antibody (clone LST1/02), Clone: LST1/02 |
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| APR12482G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A Monoclonal antibody against Human LST1 (clone LST1/02). The antibodies are raised in Mouse and are from clone LST1/02. This antibody is applicable in WB and IHC-P, ICC, IP |
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Recombinant Human P53 R175H (HLA-A*02:01) Complex Protein |
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| RP02688 | Abclonal | 500μg | EUR 304.66 |
Biotinylated Recombinant Human P53 WT (HLA-A*02:01) Complex Protein |
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| RP02756 | Abclonal | 500μg | EUR 488.87 |
JBJ-04-125-02 |
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| 558957 | MedKoo Biosciences | 500.0mg | EUR 3650 |
WSID 02 AO LOTO |
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| 833773 | BRADY NV | Piece of 1 Piece(s) | EUR 14.81 |
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Description: Description Dutch: Nood-ID-tag voor werknemers; Description French: Etiquette d’identification d’urgence pour les employés |
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JH-XI-10-02 |
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| 407891 | MedKoo Biosciences | 5.0mg | EUR 550 |
JBJ-03-142-02 |
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| 462088 | MedKoo Biosciences | 10.0mg | EUR 409 |
TG 02 (SB 1317) |
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| MBS132702-100mg | MyBiosource | 100mg | EUR 1065 |
TG 02 (SB 1317) |
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| MBS132702-500mg | MyBiosource | 500mg | EUR 2775 |
JH-VIII-157-02 |
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| HY-112140 | MedChemExpress | 10mM/1mL | EUR 2684.02 |
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Description: JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells. |
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JBJ-04-125-02 |
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| HY-135805 | MedChemExpress | Get quote | Ask for price |
|
Description: JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities[1]. |
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JBJ-02-112-05 |
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| HY-135914 | MedChemExpress | Get quote | Ask for price |
|
Description: JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 15 nM for EGFRL858R/T790M[1]. |
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JH-XI-10-02 |
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| HY-111518 | MedChemExpress | 1 mg | EUR 1569.29 |
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Description: JH-XI-10-02 is a PROTAC connected by ligands for Cereblon and CDK. JH-XI-10-02 is a highly potent and selective PROTAC CDK8 degrader, with an IC50 of 159 nM. JH-XI-10-02 causes proteasomal degradation, does not affect CDK8 mRNA levels. JH-XI-10-02 shows no effect on CDK19[1]. |
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castaneum develops resistance rapidly to many classes of insecticides including organophosphates, methyl carbamates, pyrethroids, neonicotinoids and insect growth regulators such as chitin synthesis inhibitors, it is further a suitable test system for studying resistance mechanisms. In this review, we will summarize recent advances in research focusing on the mode of action of insecticides and mechanisms of resistance identified using T. castaneum as a pest model.